U principu, lečenje ne bi smelo da traje duže od 8-12 nedelja, uključujući i interval postepene obustave leka. Lečenje se ne sme produžavati bez prethodne reevaluacije stanja pacijenta.
Parenteralna primena diazepama (ampule za injekcije ili infuziju) preporučuje se samo kod odraslih dok je kod dece bezbednija peroralna primena odnosno upotreba tableta.
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Usporen metabolizam diazepama dovodi do produženja poluvremena eliminacije i povećanja koncentracije diazepama u plazmi. Usporena je eliminacija N-demetil metabolita diazepama, što može značajno pojačati sedativni efekat. Povećan je rizik od inhibicije CNS, npr. sedacije.
In selecting to implement a medicine, the hazards of using the medication have to be weighed towards the good it's going to do. This is often a call you and your health practitioner is likely to make. For this medication, the following ought to be considered:
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It’s dangerous to consider any benzodiazepine that hasn’t been prescribed for you Even when you Assume it’s legit and if it’s a phony benzodiazepine pill it'd consist of all sorts of probably perilous substances.
you might be respiration quite rapidly or struggling to breathe (chances are you'll develop into quite wheezy or really feel such as you're choking or gasping for air)
As soon as Actual physical dependence to benzodiazepines have produced, termination of cure is going check here to be accompanied by withdrawal indications. The risk is much more pronounced in people on extensive-phrase therapy.
Abide by @SW_Londoner Public Wellness England (PHE) issued a warning about a lethal batch of unlawful medicine now in circulation through the UK. The hazardous tablets are increasingly being sold illicitly as benzodiazepines, that are authentically prescribed to deal with anxiety or sleeplessness. PHE
TolerancijaNakon ponavljane primene leka tokom nekoliko nedelja može doći do gubitka njegove efikasnosti. Granice tolerancije kod pacijenata sa organskim promenama na mozgu (posebno arteriosklerozom) ili kardiorespiratornom insuficijencijom, mogu biti veoma široke ; kod takvih pacijenata doza se mora pažljivo prilagoditi.
Inform your pharmacist or health practitioner if you're taking some other check here medicines, like herbal cures, nutritional vitamins or health supplements.
Clear away fingers through the cheek. In case the film is spit out or blown out immediately, give A different dose using a new movie. Do not give this medication with liquids.